Grey's Anatomy

Season 4

17 episodes 23 seasons

Enter a world of change in the irresistible and unforgettable fourth season of Grey's Anatomy. Love, lies, and family ties are revealed as the surgeons of Seattle Grace discover that their choices have major unintended consequences. And coupled with the arrival of some very eager new interns, life at the hospital sizzles with more emotion, excitement, and heartbreak than ever before.

Release Date

Premiered

Grey's Anatomy Season 4 released on September 27, 2007.

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S04E01 Aired September 27, 2007

A Change Is Gonna Come

Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her.

S04E02 Aired October 04, 2007

Love/Addiction

A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Alex investigates the cause of the incident by talking to a really old guy who lived in the building. Jane Burke shows up to deal with what her son left behind. Lexie tries to talk to Meredith. Callie is overwhelmed by her new position while Bailey is searching for things to do.

S04E03 Aired October 11, 2007

Let the Truth Sting

The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unless Mark and Richard can perform a radical new surgery. George impresses the other interns at work but at home he is trying to deal with his guilt about having sex with Izzie.

S04E04 Aired October 18, 2007

The Heart of the Matter

A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father and surgery for an injury he sustained while playing the game. Another patient's, named Courtney, finds out that her cancer is back.

S04E05 Aired October 25, 2007

Haunt You Every Day

It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers for what most of the doctors believe is an unnecessary surgery. One of the patients is in the hospital because they tried to carve a pumpkin in an unconventional manner.

S04E06 Aired November 01, 2007

Kung Fu Fighting

A patient comes to the ER with a dream and a condition which may prevent him from realizing it. Two patients are competing to win something big. One of them convinces an intern to take their place.

S04E07 Aired November 08, 2007

Physical Attraction… Chemical Reaction

Two arguing parents, who are named Jane and Don, bring their son in because he swallowed coins, while a middle aged woman comes in wanting cosmetic surgery on her chin. A father worries about raising a child alone when the mother needs surgery.

S04E08 Aired November 15, 2007

Forever Young

There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad goes to visit her at the hospital.

S04E09 Aired November 22, 2007

Crash into Me (1)

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.

S04E10 Aired December 06, 2007

Crash into Me (2)

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles to balance her personal life with her work.

S04E11 Aired January 10, 2008

Lay Your Hands on Me

George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn't inspire hope or happiness in her. Alex treats a faith healer.

S04E12 Aired April 24, 2008

Where the Wild Things Are

Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. The doctor's are in the midst of a competition.

S04E13 Aired May 01, 2008

Piece of My Heart

Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developments.

S04E14 Aired May 08, 2008

The Becoming

The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Christina is affected by Burke's career developments.

S04E15 Aired May 15, 2008

Losing My Mind

Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Christina continues to act strange.

S04E16 Aired May 22, 2008

Freedom (1)

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

S04E17 Aired May 22, 2008

Freedom (2)

Meredith and Derek get one last shot at success in their clinical trial; the surgeons work together to free a boy from a block of cement; Izzie helps Alex care for Rebecca; Lexie uncovers critical information about George's status as an intern.