Grey's Anatomy

Season 12

24 episodes 23 seasons

The doctors find themselves simmering in a world of sexual politics. Bailey struggles with what it means to be a woman in charge of the hospital and her husband, while Maggie faces the challenges of dating a younger man and Amelia battles her own demons. Meanwhile, in the wake of a brutal attack, Meredith finds comfort and love in the most unexpected place, Callie and Arizona find themselves in a fight for their lives, and tensions run high when Amelia and Meredith come face to face with the doctor responsible for Derek's death.

Release Date

Premiered

Grey's Anatomy Season 12 released on September 24, 2015.

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S12E01 Aired September 24, 2015

Sledgehammer

Seattle Grace Hospital springs into action to save the lives of two young girls whose powerful story will force some of the doctors to revisit the effects of bullying on their own pasts. Meanwhile, Meredith must adjust to changes at home with her new roommates while Bailey continues to fight for the Chief of Surgery position and Jackson prepares for April’s return to Seattle.

S12E02 Aired October 01, 2015

Walking Tall

The pressure is on as a determined Bailey tackles her first day as Chief; meanwhile, April's marriage is in jeopardy and she finds herself unable to address her problems; Meredith struggles to juggle all her responsibilities and Amelia works to define her relationship with Owen.

S12E03 Aired October 08, 2015

I Choose You

Maggie reevaluates her life choices after receiving an invitation to her ex-boyfriend’s wedding; Richard questions Bailey’s loyalty, and Jo confides in Stephanie about a secret she’s been keeping from Alex. Meanwhile, Alex struggles with making a difficult decision that will affect the lives of newborn twins.

S12E04 Aired October 15, 2015

Old-Time Rock-and-Roll

Owen suggests the interns learn a vital lesson on how to break bad news to patients’ families, and Arizona’s 90-year-old patient reassures her that she’s destined to find love again. Meanwhile, the sisters completely forget about the dinner party they’re hosting for everyone.

S12E05 Aired October 22, 2015

Guess Who's Coming to Dinner

In the midst of the sisters’ dinner party, Maggie ditches her cooking duties to rush to the hospital. Meanwhile, April steps in to help cook as an attempt to avoid Jackson, and Arizona nervously waits to find out more about Callie’s new girlfriend.

S12E06 Aired November 05, 2015

The Me Nobody Knows

Grey Sloan Memorial not only welcomes a new transfer resident, but also a patient who's the topic of converstation after accidentally sending his sex tape to his entire congregation. Meanwhile, Richard wrestles with how to progress his relationship with Maggie when an old friend visits the hospital, and April brings in a case of a young boy from the Middle-East.

S12E07 Aired November 12, 2015

Something Against You

The team of doctors work on a high stakes case of a long time patient, adding additional pressure to an already tense environment. Meanwhile Bailey wants Ben to kick out their new roommate, and Arizona is eager to get back into the dating world with a new wingman.

S12E08 Aired November 19, 2015

Things We Lost in the Fire

As the rumor mill around the hospital continues to spiral out of control, Grey Sloan Memorial is flooded with injured firefighters from a nearby wildfire. Maggie struggles to keep things with Andrew professional at work; meanwhile, Jo questions Alex’s priorities.

S12E09 Aired February 11, 2016

The Sound of Silence

Meredith is brutally attacked by a patient, and Penny is the one who discovers her. The doctors of Grey Sloan Memorial rush to stabilize Meredith and remain by her side in the harrowing aftermath.

S12E10 Aired February 18, 2016

All I Want Is You

As the hospital deals with Meredith's trauma, Callie and Maggie perform a risky, experimental surgery on Alex's 15-year-old patient against his professional opinion. Meanwhile, Owen and Nathan are still at odds with each other, and Maggie and Andrew's relationship continues to develop.

S12E11 Aired February 25, 2016

Unbreak My Heart

The evolution of April and Jackson's relationship is revealed through a series of flashbacks dating back to when they first met. Simultaneously, we follow the years-long progress of one of Jackson's patients.

S12E12 Aired March 03, 2016

My Next Life

A patient from Meredith's very first surgery as an Intern is readmitted to Grey Sloan Memorial with a new aneurysm, and Amelia takes her case. Meanwhile, Maggie suspects that Richard knows about her relationship with Andrew, and Arizona debates dating again.

S12E13 Aired March 10, 2016

All Eyez on Me

Meredith, Bailey, Jackson, Callie and Jo travel to a military hospital to perform an extraordinary and extremely risky surgery on a veteran with an advanced tumor. Meanwhile back at Grey Sloan, Andrew is tired of being Maggie’s worst kept secret; Ben makes an impulsive surgical decision; and a team of cheerleaders wreak havoc in the ER.

S12E14 Aired March 17, 2016

Odd Man Out

Richard throws everyone for a loop when he switches the resident and attending pairings, and Arizona takes a huge risk on a woman who is pregnant with quadruplets. Meanwhile, April is faced with a difficult decision.

S12E15 Aired March 24, 2016

I Am Not Waiting Anymore

Jackson learns about April’s pregnancy, while Alex and the team of doctors handles an hours-long triple-organ transplant surgery. Meredith considers dating again, and Andrew insists on not receiving special treatment after he and Maggie go public.

S12E16 Aired March 31, 2016

When It Hurts So Bad

Meredith regrets taking a step forward with Will; Maggie feels disconnected from Andrew; Amelia takes another look at her relationship with Owen; Catherine shakes things up for April and Jackson.

S12E17 Aired April 07, 2016

I Wear the Face

Meredith goes on an ambulance ride with Owen and Nathan to pick up a heart for a transplant patient. Musician & MS patient Kyle Diaz is admitted to Grey Sloan Memorial with a tremor in his hand, and the residents apply for the Preminger Grant. Meanwhile, Catherine continues to insert herself into Jackson and April's business against Richard's wishes.

S12E18 Aired April 14, 2016

There's a Fine, Fine Line

After a missing child forces the hospital into lockdown, Ben decides to operate on a pregnant mother without the proper surgical equipment. Miranda, as Chief, is faced with the repercussions of the event and whether or not Ben's impulsive actions were justified.

S12E19 Aired April 14, 2016

It's Alright, Ma (I'm Only Bleeding)

Miranda continues to deal with the aftermath of Ben's reckless decision and forms an advisory committee to recommend proper disciplinary action against him. Meanwhile, April and Jackson try to put their differences aside for the sake of their baby, and Arizona makes a decision that could affect her relationship with Callie forever.

S12E20 Aired April 21, 2016

Trigger Happy

The doctors work frantically to save a young boy who was accidentally shot. Meanwhile, Arizona is upset when Callie tries to make an important decision about Sofia’s future without consulting her

S12E21 Aired April 28, 2016

You're Gonna Need Someone on Your Side

Stephanie’s relationship with Kyle becomes complicated. Meanwhile, Meredith encourages Amelia and Owen to take a chance and choose to be a real couple. Arizona and Callie are at odds and put their friends in the middle of an uncomfortable situation.

S12E22 Aired May 05, 2016

Mama Tried

Callie and Arizona are at odds over Sofia’s future, and Stephanie questions the status of her relationship with Kyle. Meanwhile, Alex and April work on a pregnant teen that is readmitted to Grey Sloan Memorial.

S12E23 Aired May 12, 2016

At Last

Owen and Amelia take their relationship to the next level; Alex gains some clarity on his future with Jo; and Callie and Arizona continue to struggle with the current custody arrangement.

S12E24 Aired May 19, 2016

Family Affair

Meredith and Maggie support Amelia on an important day; Jo reveals that she has been keeping secrets from Alex while Arizona and Callie deal with the impact of their custody arrangement. Meanwhile, Ben leaps into action to help a friend.